A recent study published in JAMA Network Open delves into the impact of cannabis use on brain function during cognitive tasks, both in recent and lifetime users. This study, the largest of its kind, involved over 1,000 young adults aged 22 to 36 and utilized brain imaging technology to assess the effects of cannabis use.
The findings revealed that heavy lifetime cannabis users, as well as recent users, exhibited reduced brain activity during a working memory task. Working memory is crucial for tasks that involve retaining and utilizing information to perform various activities. The decline in brain activity was associated with poorer performance on working memory tasks.
Lead author of the study, Joshua Gowin, Ph.D., emphasized the importance of understanding the implications of cannabis use on human health as its popularity continues to grow worldwide. The study classified heavy users as individuals who have used cannabis over 1,000 times in their lifetime, with moderate users falling between 10 to 999 times and nonusers having used less than 10 times.
During the study, participants underwent magnetic resonance imaging (MRI) sessions and were given seven cognitive tasks to complete. The results indicated a significant impact of cannabis on brain function during working memory tasks, with observed effects in both recent and lifetime users. The impact was less pronounced in other cognitive tasks.
The study highlighted that heavy cannabis use led to reduced brain activity in specific regions associated with cognitive functions such as decision-making, memory, attention, and emotional processing. However, the research also suggested that abstaining from cannabis use before engaging in cognitive tasks could potentially improve performance.
Gowin emphasized the need for further research to understand the long-term effects of cannabis on brain function and its impact on different age groups. He also stressed the importance of individuals being aware of their cannabis use and how it may affect their cognitive abilities.
In conclusion, the study underscores the need for comprehensive studies to explore the effects of cannabis on brain function. By gaining a deeper understanding of these effects, individuals can make informed decisions regarding cannabis use and its potential consequences.
For more information, you can refer to the study published in JAMA Network Open titled “Brain Function Outcomes of Recent and Lifetime Cannabis Use” (2025) with DOI: 10.1001/jamanetworkopen.2024.57069. This research was conducted by the CU Anschutz Medical Campus.
This article was originally published on MedicalXpress and is subject to copyright. Please seek permission before reproducing any part of the content for private study or research purposes.
